People


Meet the Lab

J. Manuel Hernández-Hernández, PhD

Principal Investigator, Professor.

J. Manuel Hernández, PhD, is a full time Professor of Genetics and Molecular Biology at the Centre for Research and Advanced Studies (CINVESTAV) in México City.

Dr. Hernández earned his PhD in Biomedical Sciences from the National Autonomous University of Mexico. He then joined the lab of Professor Anthony N. Imbalzano at the University of Massachusetts Medical School to study transcriptional regulation during skeletal myogenesis. Later on, he worked as research associate in the laboratory of Dr. Michael Rudnicki at the Sprott Centre for Stem Cell Research in Ottawa, Canada, where he focused on the study of transcriptional regulation, long-range chromatin organization and genome topology controlling muscle stem cells function.

In 2018, Dr. Hernández established his independent research group at the Department of Genetics and Molecular Biology.

Rodolfo Daniel Ávila-Avilés

PhD Student

Daniel earned his undergraduate degree in Biotechnology from the Autonomous University of the State of Mexico and Philosophy from the Vasco de Quiroga University. He completed a Masters in Genetics and Molecular Biology at Cinvestav. As a PhD student in the Hernández Lab, Daniel´s research focuses on resolving the interactome associated with the mutant-ATXN7 mRNA in the context of Spinocerebellar Ataxia Type 7 (SCA7), using CRISPR-Cas13 technology.

Daniel also contributes in the identification of small molecules with potential activity in muscle differentiation and regeneration through molecular docking and molecular dynamics.

Juan Enrique Chacón-Hernández

PhD Student

Juan Enrique is from Ciudad Juárez, Chihuahua, Mexico. He earned his undergraduate degree in Biology at the Autonomous University of Ciudad Juarez studying mosquito populations and molecular detection of viruses. Enrique completed his Master's in Biomedicine, studying the potential of sulfated polysaccharides with antiviral activity.

Enrique's main project in the lab aims to characterize the mechanisms mediating muscle fiber type specification and the effect of small molecules on muscle plasticity.

Out of the lab Enrique spends his time reading, watching TV series and making different types of tea...also playing video games from time to time.



Amairani Cancino-Bello

Master's Student

Amairani is from Guerrero, México. She earned her undergraduate degree in Molecular Biology from the Autonomous University of México, in México City.

Her research focuses on the study of long non-coding RNAs with regulatory functions in skeletal muscle differentiation.


Ingrid Aimée Chagolla-Badillo

Master's Student

Aimée is from Guanajuato, México where she earned her undergraduate degree in Experimental Biology.

Aimée's interests in the lab are the characterization of microRNAs that modulate fiber type identity in response to the flavonol Epicatechin in wild type and dystrophic mouse models.

Mauricio Hernández-Somilleda

Master's Student


Mauricio is from México City. He earned his bachelor's in Biotechnology from the Autonomous University of Guadalajara.

Mauricio's project focuses on applying CRISPR-Cas9 technology to identify chromatin remodeling complexes and transcription factors present at gene regulatory elements that control expression of genes important for skeletal muscle regeneration.


Ana Victoria Arredondo-Robles

Undergraduate Student

Victoria is currently working on the identification and characterization of novel new small molecules with the potential to enhance muscle differentiation and regeneration, applying molecular docking and molecular dynamics.


Jorge Enrique Balderas-Sánchez

Undergraduate Student

As a part of his undergraduate internship in Biotechnology, Enrique is currently working on the identification and characterization of novel new small molecules with the potential to enhance muscle differentiation and regeneration, applying molecular docking and molecular dynamics.

Outside the lab, Enrique enjoys biking, outdoors activities, going to the movies and playing video games.

Manuel Gutiérrez-Rodríguez

Undergraduate Student


Manuel is currently working on the identification and characterization of novel new small molecules with the potential to enhance muscle differentiation and regeneration, applying molecular docking and molecular dynamics.


Leticia Alemán-Lazarini

Lab Technician



Lab Alumni


Lawrence Christopher López-Méndez, Master's Student

Kevin Ruiz-Fajardo, Master's Student

Claudia Negrón-Lomas, Master's Student